Browse

Avian Biotechnology: Insights from Germ Cell-mediated Transgenic Systems

Cited 9 time in Web of Science Cited 6 time in Scopus
Authors
Song, Gwonhwa; Park, Tae Sub; Kim, Tae Min; Han, Jae Yong
Issue Date
2010
Publisher
Japan Poultry Science Association
Citation
Journal- Poultry Science, vol.47 no.3, pp. 197-207
Keywords
animal biomodelbioreactorgerm cellstransgenic fowl
Abstract
Aves species have become valuable models for numerous experimental and biotechnological purposes due to their unique embryological and physiological traits. This review integrates recent progress and new insights into the molecular and physiological mechanisms of transgenic fowl production. Recent reports have indicated that birds are essential for studying vertebrate development and the conservation of endangered bird species, as well as serving as bioreactor hens. Over the last decade, germ cells and genetic modification have become pivotal components for the production of transgenic animals. Three prerequisites must be met for successfully producing transgenic fowl: the e ective manipulation of various types of avian pluripotent cells without the loss of di erentiation capacity, the manipulation of genes of interest without altering normal gene function, and increasing the e ciency of germ line chimera production. An understanding of the cellular and molecular signals that regulate germ cells as well as the development of a stable gene delivery method will make these species indispensable tools for basic research and biotechnological applications.
ISSN
1346-7395
Language
English
URI
https://hdl.handle.net/10371/100290
DOI
https://doi.org/10.2141/jpsa.009108
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Food and Animal Biotechnology (식품·동물생명공학부)Journal Papers (저널논문_식품·동물생명공학부)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse