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Identification of Loci at 1q21 and 16q23 That Affect Susceptibility to Inflammatory Bowel Disease in Koreans
DC Field | Value | Language |
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dc.contributor.author | Yang, Suk-Kyun | - |
dc.contributor.author | Hong, Myunghee | - |
dc.contributor.author | Oh, Hyunjung | - |
dc.contributor.author | Low, Hui-Qi | - |
dc.contributor.author | Jung, Seulgi | - |
dc.contributor.author | Ahn, Seonjoo | - |
dc.contributor.author | Kim, Youngjin | - |
dc.contributor.author | Baek, Jiwon | - |
dc.contributor.author | Lee, Cue Hyunkyu | - |
dc.contributor.author | Kim, Eunji | - |
dc.contributor.author | Kim, Kyung Mo | - |
dc.contributor.author | Ye, Byong Duk | - |
dc.contributor.author | Kim, Kyung-Jo | - |
dc.contributor.author | Park, Sang Hyoung | - |
dc.contributor.author | Lee, Ho-Su | - |
dc.contributor.author | Lee, Inchul | - |
dc.contributor.author | Shin, Hyoung Doo | - |
dc.contributor.author | Han, Buhm | - |
dc.contributor.author | McGovern, Dermot P. B. | - |
dc.contributor.author | Liu, Jianjun | - |
dc.contributor.author | Song, Kyuyoung | - |
dc.date.accessioned | 2023-04-26T05:09:06Z | - |
dc.date.available | 2023-04-26T05:09:06Z | - |
dc.date.created | 2018-08-16 | - |
dc.date.created | 2018-08-16 | - |
dc.date.created | 2018-08-16 | - |
dc.date.created | 2018-08-16 | - |
dc.date.issued | 2016-12 | - |
dc.identifier.citation | Gastroenterology, Vol.151 No.6, pp.1096-1099.e3 | - |
dc.identifier.issn | 0016-5085 | - |
dc.identifier.uri | https://hdl.handle.net/10371/191569 | - |
dc.description.abstract | Recent genome-wide association studies have identified more than 200 regions that affect susceptibility to inflammatory bowel disease (IBD). However, identified common variants account for only a fraction of IBD heritability and largely have been identified in populations of European ancestry. We performed a genome-wide association study of susceptibility loci in Korean individuals, comprising a total of 1505 IBD patients and 4041 controls. We identified 2 new susceptibility loci for IBD at genome-wide significance: rs3766920 near PYGO2-SHC1 at 1q21 and rs16953946 in CDYL2 at 16q23. In addition, we confirmed associations, in Koreans, with 28 established IBD loci (P < 2.16 3 10(-4)). Our findings support the complementary value of genetic studies in different populations. | - |
dc.language | 영어 | - |
dc.publisher | W. B. Saunders Co., Ltd. | - |
dc.title | Identification of Loci at 1q21 and 16q23 That Affect Susceptibility to Inflammatory Bowel Disease in Koreans | - |
dc.type | Article | - |
dc.identifier.doi | 10.1053/j.gastro.2016.08.025 | - |
dc.citation.journaltitle | Gastroenterology | - |
dc.identifier.wosid | 000390955500023 | - |
dc.identifier.scopusid | 2-s2.0-84997132283 | - |
dc.citation.endpage | 1099.e3 | - |
dc.citation.number | 6 | - |
dc.citation.startpage | 1096 | - |
dc.citation.volume | 151 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Han, Buhm | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | GENOME-WIDE ASSOCIATION | - |
dc.subject.keywordPlus | GENETIC SUSCEPTIBILITY | - |
dc.subject.keywordPlus | COMPLEX DISEASES | - |
dc.subject.keywordPlus | CROHNS-DISEASE | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | POPULATIONS | - |
dc.subject.keywordPlus | COLITIS | - |
dc.subject.keywordPlus | ASIA | - |
dc.subject.keywordAuthor | Crohn&apos | - |
dc.subject.keywordAuthor | s Disease | - |
dc.subject.keywordAuthor | Ulcerative Colitis | - |
dc.subject.keywordAuthor | Genetics | - |
dc.subject.keywordAuthor | Risk Factor | - |
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