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A novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces sp
Cited 12 time in
Web of Science
Cited 14 time in Scopus
- Authors
- Issue Date
- 2006-08-16
- Publisher
- Elsevier
- Citation
- Bioorg Med Chem Lett. 2006 Nov 1;16(21):5643-5. Epub 2006 Aug 14.
- Keywords
- Antineoplastic Agents/chemistry/pharmacology ; Butanols/chemistry/*pharmacology ; Cell Proliferation/*drug effects ; Hela Cells ; Humans ; Pyridines/chemistry/*pharmacology ; Streptomyces
- Abstract
- A novel compound showing antiproliferative effect was isolated from Streptomyces sp. Its structure was determined based on the interpretation of the NMR spectra, and its conformation was elucidated using molecular modeling and 2D NOESY. It was determined to be (E)-4-phenyl-3-(pyridine-2-yl)but-2-en-1-ol.
- ISSN
- 0960-894X (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16908144
https://hdl.handle.net/10371/36284
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