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Showing results 121 to 180 of 180

Issue Date	Title / Author(s) / Citation	File
2018-01	Targeted knockout of a chemokine-like gene increases anxiety and fear responses Choi, Jung-Hwa; Jeong, Yun-Mi; Kim, Sujin; Lee, Boyoung; Ariyasiri, Krishan; Kim, Hyun-Taek; Jung, Seung-Hyun; Hwang, Kyu-Seok; Choi, Tae-Ik; Park, Chul O.; Huh, Won-Ki; Carl, Matthias; Rosenfeld, Jill A.; Raskin, Salmo; Ma, Alan; Gecz, Jozef; Kim, Hyung-Goo; Kim, Jin-Soo; Shin, Ho-Chul; Park, Doo-Sang; Gerlai, Robert; Jamieson, Bradley B.; Kim, Joon S.; Iremonger, Karl J.; Lee, Sang H.; Shin, Hee-Sup; Kim, Cheol-Hee Proceedings of the National Academy of Sciences of the United States of America, Vol.115 No.5, pp.E1041-E1050	DOI
2018-03	Microbial warfare against viruses Many new antiviral defense systems are found in bacteria and archaea Kim, Jin-Soo Science, Vol.359 No.6379, pp.993-993	DOI
2018-03	CRISPR RNAs trigger innate immune responses in human cells Kim, Sojung; Koo, Taeyoung; Jee, Hyeon-Gun; Cho, Hee-Yeon; Lee, Gyeorae; Lim, Dong-Gyun; Shin, Hyoung Shik; Kim, Jin-Soo Genome Research, Vol.28 No.3, pp.367-373	view file DOI
2018-03	Precision genome engineering through adenine and cytosine base editing Kim, Jin-Soo Nature Plants, Vol.4 No.3, pp.148-151	DOI
2018-03	Microbial warfare against viruses Many new antiviral defense systems are found in bacteria and archaea Kim, Jin-Soo Science, Vol.359 No.6379, pp.993-993	DOI
2018-04	Structural insights into the apo-structure of Cpf1 protein from Francisella novicida Min, Kyungjin; Yoon, Hyunjun; Jo, Inseong; Ha, Nam-Chul; Jin, Kyeong Sik; Kim, Jin-Soo; Lee, Hyung Ho Biochemical and Biophysical Research Communications, Vol.498 No.4, pp.775-781	DOI
2018-04	Response to "unexpected mutations after CRISPR-Cas9 editing in vivo Kim, Sang-Tae; Park, Jeongbin; Kim, Daesik; Kim, Kyoungmi; Bae, Sangsu; Schlesner, Matthias; Kim, Jin-Soo Nature Methods, Vol.15 No.4, pp.239-240	DOI
2018-04	Response to "unexpected mutations after CRISPR-Cas9 editing in vivo" Kim, Sang-Tae; Park, Jeongbin; Kim, Daesik; Kim, Kyoungmi; Bae, Sangsu; Schlesner, Matthias; Kim, Jin-Soo Nature Methods, Vol.15 No.4, pp.239-240	DOI
2018-05	Long terminal repeat CRISPR-CAR-coupled "Universal" T cells mediate potent anti-leukemic effects Georgiadis, Christos; Preece, Roland; Nickolay, Lauren; Etuk, Aniekan; Petrova, Anastasia; Ladon, Dariusz; Danyi, Alexandra; Humphryes-Kirilov, Neil; Ajetunmobi, Ayokunmi; Kim, Daesik; Kim, Jin-Soo; Qasim, Waseem Molecular Therapy, Vol.26 No.5, pp.1215-1227	DOI
2018-06	Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection Kim, Heon Seok; Lee, Kyungjin; Kim, Seong-Jun; Cho, Sungchan; Shin, Hye Jin; Kim, Chonsaeng; Kim, Jin-Soo Genome Research, Vol.28 No.6, pp.859-868	view file DOI
2018-06	Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using campylobacter jejuni Cas9 Koo, Taeyoung; Lu-Nguyen, Ngoc B.; Malerba, Alberto; Kim, Eunji; Kim, Daesik; Cappellari, Ornella; Cho, Hee-Yeon; Dickson, George; Popplewell, Linda; Kim, Jin-Soo Molecular Therapy, Vol.26 No.6, pp.1529-1538	DOI
2018-06	Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy Ryu, Seuk-Min; Koo, Taeyoung; Kim, Kyoungmi; Lim, Kayeong; Baek, Gayoung; Kim, Sang-Tae; Kim, Heon Seok; Kim, Da-eun; Lee, Hyunji; Chung, Eugene; Kim, Jin-Soo Nature Biotechnology, Vol.36 No.6, pp.536-539	DOI
2018-07	Precision genome engineering through adenine base editing in plants Kang, Beum-Chang; Yun, Jae-Young; Kim, Sang-Tae; Shin, YouJin; Ryu, Jahee; Choi, Minkyung; Woo, Je Wook; Kim, Jin-Soo Nature Plants, Vol.4 No.7, pp.427-431	DOI
2018-07	Sometimes you're the scooper, and sometimes you get scooped: How to turn both into something good Kim, Jin-Soo; Corn, Jacob E. PLoS Biology, Vol.16 No.7, p. e2006843	view file DOI
2018-07	Direct observation of DNA target searching and cleavage by CRISPR-Cas12a Jeon, Yongmoon; Choi, You Hee; Jang, Yunsu; Yu, Jihyeon; Goo, Jiyoung; Lee, Gyejun; Jeong, You Kyeong; Lee, Seung Hwan; Kim, In-San; Kim, Jin-Soo; Jeong, Cherlhyun; Lee, Sanghwa; Bae, Sangsu Nature Communications, Vol.9, p. 2777	view file DOI
2018-08	Ma et al. reply Ma, Hong; Marti-Gutierrez, Nuria; Park, Sang-Wook; Wu, Jun; Hayama, Tomonari; Darby, Hayley; Van Dyken, Crystal; Li, Ying; Koski, Amy; Liang, Dan; Suzuki, Keiichiro; Gu, Ying; Gong, Jianhui; Xu, Xun; Ahmed, Riffat; Lee, Yeonmi; Kang, Eunju; Ji, Dongmei; Park, A-Reum; Kim, Daesik; Kim, Sang-Tae; Heitner, Stephen B.; Battaglia, David; Krieg, Sacha A.; Lee, David M.; Wu, Diana H.; Wolf, Don P.; Amato, Paula; Kaul, Sanjiv; Belmonte, Juan Carlos Izpisua; Kim, Jin-Soo; Mitalipov, Shoukhrat Nature, Vol.560 No.7717, pp.E10-E23	DOI
2018-08	Unexpected CRISPR on-target effects Lee, Hyunji; Kim, Jin-Soo Nature Biotechnology, Vol.36 No.8, pp.703-704	DOI
2018-08	Ma et al. reply Ma, Hong; Marti-Gutierrez, Nuria; Park, Sang-Wook; Wu, Jun; Hayama, Tomonari; Darby, Hayley; Van Dyken, Crystal; Li, Ying; Koski, Amy; Liang, Dan; Suzuki, Keiichiro; Gu, Ying; Gong, Jianhui; Xu, Xun; Ahmed, Riffat; Lee, Yeonmi; Kang, Eunju; Ji, Dongmei; Park, A-Reum; Kim, Daesik; Kim, Sang-Tae; Heitner, Stephen B.; Battaglia, David; Krieg, Sacha A.; Lee, David M.; Wu, Diana H.; Wolf, Don P.; Amato, Paula; Kaul, Sanjiv; Belmonte, Juan Carlos Izpisua; Kim, Jin-Soo; Mitalipov, Shoukhrat Nature, Vol.560 No.7717, pp.E10-E23	DOI
2018-08	Unexpected CRISPR on-target effects Lee, Hyunji; Kim, Jin-Soo Nature Biotechnology, Vol.36 No.8, pp.703-704	DOI
2018-08	Directed evolution of CRISPR-Cas9 to increase its specificity Lee, Jungjoon K.; Jeong, Euihwan; Lee, Joonsun; Jung, Minhee; Shin, Eunji; Kim, Young-hoon; Lee, Kangin; Jung, Inyoung; Kim, Daesik; Kim, Seokjoong; Kim, Jin-Soo Nature Communications, Vol.9, p. 3048	view file DOI
2018-09	Author Correction: Precision genome engineering through adenine base editing in plants Kang, Beum-Chang; Yun, Jae-Young; Kim, Sang-Tae; Shin, YouJin; Ryu, Jahee; Choi, Minkyung; Woo, Je Wook; Kim, Jin-Soo Nature Plants, Vol.4 No.9, pp.730-730	DOI
2018-10	Towards therapeutic base editing Seo, Huiyun; Kim, Jin-Soo Nature Medicine, Vol.24 No.10, pp.1493-1495	DOI
2018-10	Towards therapeutic base editing Seo, Huiyun; Kim, Jin-Soo Nature Medicine, Vol.24 No.10, pp.1493-1495	DOI
2018-12	dCas9-mediated nanoelectrokinetic direct detection of target gene for liquid biopsy Lee, Hyomin; Choi, Jihye; Jeong, Euihwan; Baek, Seongho; Kim, Hee Chan; Chae, Jong-Hee; Koh, Youngil; Seo, Sang Woo; Kim, Jin-Soo; Kim, Sung Jae Nano Letters, Vol.18 No.12, pp.7642-7650	DOI
2018-12	CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration Koo, Taeyoung; Park, Sung Wook; Jo, Dong Hyun; Kim, Daesik; Kim, Jin Hyoung; Cho, Hee-Yeon; Kim, Jeungeun; Kim, Jeong Hun; Kim, Jin-Soo Nature Communications, Vol.9 No.1, p. 1855	view file DOI
2018-12	Web-based design and analysis tools for CRISPR base editing Hwang, Gue-Ho; Park, Jeongbin; Lim, Kayeong; Kim, Sunghyun; Yu, Jihyeon; Yu, Eunchong; Kim, Sang-Tae; Eils, Roland; Kim, Jin-Soo; Bae, Sangsu BMC Bioinformatics, Vol.19, p. 542	view file DOI
2018-12	DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA Kim, Daesik; Kim, Jin-Soo Genome Research, Vol.28 No.12, pp.1894-1900	view file DOI
2018-12	Machine learning finds Cas9-edited genotypes Bae, Sangsu; Kim, Jin-Soo Nature Biomedical Engineering, Vol.2 No.12, pp.892-893	DOI
2018-12	Machine learning finds Cas9-edited genotypes Bae, Sangsu; Kim, Jin-Soo Nature Biomedical Engineering, Vol.2 No.12, pp.892-893	DOI
2019-01	Technologies to watch in 2019 Teichmann, Sarah; Kim, Jin-Soo; Zhuang, Xiaowei; Zeng, Hongkui; Boeke, Jef; Ramakrishnan, Venki; Greene, Casey Nature, Vol.565 No.7740, pp.521-523	DOI
2019-01	Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus Jo, Dong Hyun; Koo, Taeyoung; Cho, Chang Sik; Kim, Jin Hyoung; Kim, Jin-Soo; Kim, Jeong Hun Molecular Therapy, Vol.27 No.1, pp.130-136	DOI
2019-01	Technologies to watch in 2019 Teichmann, Sarah; Kim, Jin-Soo; Zhuang, Xiaowei; Zeng, Hongkui; Boeke, Jef; Ramakrishnan, Venki; Greene, Casey Nature, Vol.565 No.7740, pp.521-523	DOI
2019-02	CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion Globyte, Viktorija; Lee, Seung Hwan; Bae, Taegeun; Kim, Jin-Soo; Joo, Chirlmin EMBO Journal, Vol.38 No.4, p. e99466	DOI
2019-03	Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases Kim, Daesik; Luk, Kevin; Wolfe, Scot A.; Kim, Jin-Soo Annual Review of Biochemistry, Vol.88, pp.191-220	DOI
2019-04	Genome-wide target specificity of CRISPR RNA-guided adenine base editors Kim, Daesik; Kim, Da-eun; Lee, Gyeorae; Cho, Sung-Ik; Kim, Jin-Soo Nature Biotechnology, Vol.37 No.4, pp.430-435	DOI
2019-05	CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells Gruffaz, Marion; Yuan, Hongfeng; Meng, Wen; Liu, Hui; Bae, Sangsu; Kim, Jin-Soo; Lu, Chun; Huang, Yufei; Gao, Shou-Jiang mBio, Vol.10 No.3, p. e00866-19	view file DOI
2019-08	CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors Lee, Choongil; Jo, Dong Hyun; Hwang, Gue-Ho; Yu, Jihyeon; Kim, Jin Hyoung; Park, Se-eun; Kim, Jin-Soo; Kim, Jeong Hun; Bae, Sangsu Molecular Therapy, Vol.27 No.8, pp.1364-1371	DOI
2019-08	Improving CRISPR Genome Editing by Engineering Guide RNAs Moon, Su Bin; Kim, Do Yon; Ko, Jeong-Heon; Kim, Jin-Soo; Kim, Yong-Sam Trends in Biotechnology, Vol.37 No.8, pp.870-881	view file DOI
2019-10	Generation of early-flowering Chinese cabbage (Brassica rapa spp. pekinensis) through CRISPR/Cas9-mediated genome editing Jeong, So Young; Ahn, Hyomin; Ryu, Jahee; Oh, Youngbin; Sivanandhan, Ganeshan; Won, Kang-Hee; Park, Young Doo; Kim, Jin-Soo; Kim, Hyeran; Lim, Yong Pyo; Kim, Sang-Gyu Plant Biotechnology Reports, Vol.13 No.5, pp.491-499	DOI
2019-10	Guidelines for C to T base editing in plants: base-editing window, guide RNA length, and efficient promoter Kang, Beum-Chang; Woo, Je Wook; Kim, Sang-Tae; Bae, Su-Ji; Choi, Minkyung; Kim, Jin-Soo; Kim, Sang-Gyu Plant Biotechnology Reports, Vol.13 No.5, pp.533-541	DOI
2019-10	Adenine base editors catalyze cytosine conversions in human cells Kim, Heon Seok; Jeong, You Kyeong; Hur, Junho K.; Kim, Jin-Soo; Bae, Sangsu Nature Biotechnology, Vol.37 No.10, pp.1145-1148	DOI
2019-12	Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target Park, Sung-Jin; Kim, Beomsue; Choi, Sejong; Balasubramaniam, Sivaraman; Lee, Sung-Chan; Lee, Jung Yeol; Kim, Heon Seok; Kim, Jun-Young; Kim, Jong-Jin; Lee, Yong-An; Kang, Nam-Young; Kim, Jin-Soo; Chang, Young-Tae Nature Communications, Vol.10 No.1, p. 1111	view file DOI
2020	CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells Hwang, Gue-Ho; Yu, Jihyeon; Yang, Soyeon; Son, Woo Jae; Lim, Kayeong; Kim, Heon Seok; Kim, Jin-Soo; Bae, Sangsu Computational and Structural Biotechnology Journal, Vol.18, pp.1686-1694	DOI
2020-05	Recent advances in genome editing of stem cells for drug discovery and therapeutic application Lee, Jaesuk; Bayarsaikhan, Delger; Bayarsaikhan, Govigerel; Kim, Jin-Soo; Schwarzbach, Elizabeth; Lee, Bonghee Pharmacology and Therapeutics, Vol.209, p. 107501	view file DOI
2020-05	Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages Na, Yi Rang; Kwon, Jung Won; Kim, Da Young; Chung, Hyewon; Song, Juha; Jung, Daun; Quan, Hailian; Kim, Daesik; Kim, Jin-Soo; Ju, Young Wook; Han, Wonshik; Ryu, Han Suk; Lee, Yun-Sang; Hong, Jung Joo; Seok, Seung Hyeok Cell Reports, Vol.31 No.6, p. 107643	DOI
2020-08	Genome-wide specificity of dCpf1 cytidine base editors Kim, Daesik; Lim, Kayeong; Kim, Da-eun; Kim, Jin-Soo Nature Communications, Vol.11 No.1, p. 4072	view file DOI
2021-02	Identifying genome-wide off-target sites of CRISPR RNA-guided nucleases and deaminases with Digenome-seq Kim, Daesik; Kang, Beum-Chang; Kim, Jin-Soo Nature Protocols, Vol.16 No.2, pp.1170-1192	DOI
2021-02	Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases Lee, Hyunji; Lee, Seonghyun; Baek, Gayoung; Kim, Annie; Kang, Beum-Chang; Seo, Huiyun; Kim, Jin-Soo Nature Communications, Vol.12 No.1, p. 1190	DOI
2021-02	Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing Shin, Ha Rim; See, Ji-Eun; Kweon, Jiyeon; Kim, Heon Seok; Sung, Gi-Jun; Park, Sojung; Jang, An-Hee; Jang, Gayoung; Choi, Kyung-Chul; Kim, Inki; Kim, Jin-Soo; Kim, Yongsub Nucleic Acids Research, Vol.49 No.4, pp.2390-2399	DOI
2021-06	Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing Kim, Annie; Lee, Kun-Gu; Kwon, Yeongbeen; Lee, Kang-In; Yang, Heung-Mo; Habib, Omer; Kim, Jihun; Kim, Sang-Tae; Kim, Sung Joo; Kim, Jin-Soo; Hwang, Dong-Youn Stem Cell Reviews and Reports, Vol.17 No.3, pp.1053-1067	DOI
2021-06	ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update Lovell-Badge, Robin; Anthony, Eric; Barker, Roger A.; Bubela, Tania; Brivanlou, Ali H.; Carpenter, Melissa; Charo, R. Alta; Clark, Amander; Clayton, Ellen; Cong, Yali; Daley, George Q.; Fu, Jianping; Fujita, Misao; Greenfield, Andy; Goldman, Steve A.; Hill, Lori; Hyun, Insoo; Isasi, Rosario; Kahn, Jeffrey; Kato, Kazuto; Kim, Jin-Soo; Kimmelman, Jonathan; Knoblich, Juergen A.; Mathews, Debra; Montserrat, Nuria; Mosher, Jack; Munsie, Megan; Nakauchi, Hiromitsu; Naldini, Luigi; Naughton, Gail; Niakan, Kathy; Ogbogu, Ubaka; Pedersen, Roger; Rivron, Nicolas; Rooke, Heather; Rossant, Janet; Round, Jeff; Saitou, Mitinori; Sipp, Douglas; Steffann, Julie; Sugarman, Jeremy; Surani, Azim; Takahashi, Jun; Tang, Fuchou; Turner, Leigh; Zettler, Patricia J.; Zhai, Xiaomei Stem Cell Reports, Vol.16 No.6, pp.1398-1408	DOI
2021-07	Chloroplast and mitochondrial DNA editing in plants Kang, Beum-Chang; Bae, Su-Ji; Lee, Seonghyun; Lee, Jeong Sun; Kim, Annie; Lee, Hyunji; Baek, Gayoung; Seo, Huiyun; Kim, Jihun; Kim, Jin-Soo Nature Plants, Vol.7 No.7, pp.899-905	DOI
2021-07	PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing Hwang, Gue-Ho; Jeong, You Kyeong; Habib, Omer; Hong, Sung-Ah; Lim, Kayeong; Kim, Jin-Soo; Bae, Sangsu Nucleic Acids Research, Vol.49 No.W1, pp.W499-W504	DOI
2021-11	Adenine base editor engineering reduces editing of bystander cytosines Jeong, You Kyeong; Lee, SeokHoon; Hwang, Gue-Ho; Hong, Sung-Ah; Park, Se-eun; Kim, Jin-Soo; Woo, Jae-Sung; Bae, Sangsu Nature Biotechnology, Vol.39 No.11, pp.1426-1433	DOI
2022-12	Targeted A-to-G base editing of chloroplast DNA in plants Mok, Young Geun; Hong, Sunghyun; Bae, Su-Ji; Cho, Sung-Ik; Kim, Jin-Soo Nature Plants, Vol.8 No.12, pp.1378-1384	DOI
2023-03	Prime editing with genuine Cas9 nickases minimizes unwanted indels Lee, Jaesuk; Lim, Kayeong; Kim, Annie; Mok, Young Geun; Chung, Eugene; Cho, Sung-Ik; Lee, Ji Min; Kim, Jin-Soo Nature Communications, Vol.14 No.1, p. 41467	DOI
2023-03	Limitations of gene editing assessments in human preimplantation embryos Liang, Dan; Mikhalchenko, Aleksei; Ma, Hong; Marti Gutierrez, Nuria; Chen, Tailai; Lee, Yeonmi; Park, Sang-Wook; Tippner-Hedges, Rebecca; Koski, Amy; Darby, Hayley; Li, Ying; Van Dyken, Crystal; Zhao, Han; Wu, Keliang; Zhang, Jingye; Hou, Zhenzhen; So, Seongjun; Han, Jongsuk; Park, Jumi; Kim, Chong-Jai; Zong, Kai; Gong, Jianhui; Yuan, Yilin; Gu, Ying; Shen, Yue; Olson, Susan B.; Yang, Hui; Battaglia, David; O'Leary, Thomas; Krieg, Sacha A.; Lee, David M.; Wu, Diana H.; Duell, P. Barton; Kaul, Sanjiv; Kim, Jin-Soo; Heitner, Stephen B.; Kang, Eunju; Chen, Zi-Jiang; Amato, Paula; Mitalipov, Shoukhrat Nature Communications, Vol.14 No.1, p. 1219	DOI
2023-05	In vivo application of base and prime editing to treat inherited retinal diseases Jo, Dong Hyun; Bae, Sangsu; Kim, Hyongbum Henry; Kim, Jin-Soo; Kim, Jeong Hun Progress in Retinal and Eye Research, Vol.94, p. 101132	DOI
2023-10	Synergistic Effects of Metformin and Trastuzumab on HER2 Positive Gastroesophageal Adenocarcinoma Cells In Vitro and In Vivo Kim, Jin-Soo; Kim, Mi Young; Hong, Sungyoul Cancers, Vol.15 No.19, p. 4768	DOI
2024-01	Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA Cho, Sung-Ik; Lim, Kayeong; Hong, Seongho; Lee, Jaesuk; Kim, Annie; Lim, Chae Jin; Ryou, Seungmin; Lee, Ji Min; Mok, Young Geun; Chung, Eugene; Kim, Sanghun; Han, Seunghun; Cho, Sang-Mi; Kim, Jieun; Kim, Eun-Kyoung; Nam, Ki-Hoan; Oh, Yeji; Choi, Minkyung; An, Tae Hyeon; Oh, Kyoung-Jin; Lee, Seonghyun; Lee, Hyunji; Kim, Jin-Soo Cell, Vol.187 No.1, pp.95-109.e26	DOI

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