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Showing results 1 to 43 of 43

Issue Date	Title / Author(s) / Citation	File
2014-01	Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases Cho, Seung Woo; Kim, Sojung; Kim, Yongsub; Kweon, Jiyeon; Kim, Heon Seok; Bae, Sangsu; Kim, Jin-Soo Genome Research, Vol.24 No.1, pp.132-141	DOI
2014-05	Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases Bae, Sangsu; Park, Jeongbin; Kim, Jin-Soo Bioinformatics, Vol.30 No.10, pp.1473-1475	DOI
2014-07	Microhomology-based choice of Cas9 nuclease target sites Bae, Sangsu; Kweon, Jiyeon; Kim, Heon Seok; Kim, Jin-Soo Nature Methods, Vol.11 No.7, pp.705-706	DOI
2015-03	Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells Kim, Daesik; Bae, Sangsu; Park, Jeongbin; Kim, Eunji; Kim, Seokjoong; Yu, Hye Ryeong; Hwang, Jinha; Kim, Jong-Il; Kim, Jin-Soo Nature Methods, Vol.12 No.3, pp.237-243	DOI
2015-08	Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9 Park, Chul-Yong; Kim, Duk Hyoung; Son, Jeong Sang; Sung, Jin Jea; Lee, Jaehun; Bae, Sangsu; Kim, Jong-Hoon; Kim, Dong-Wook; Kim, Jin-Soo Cell Stem Cell, Vol.17 No.2, pp.213-220	DOI
2015-12	Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites Park, Jeongbin; Bae, Sangsu; Kim, Jin-Soo Bioinformatics, Vol.31 No.24, pp.4014-4016	DOI
2016-07	Site-directed mutagenesis in Petunia x hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins Subburaj, Saminathan; Chung, Sung Jin; Lee, Choongil; Ryu, Seuk-Min; Kim, Duk Hyoung; Kim, Jin-Soo; Bae, Sangsu; Lee, Geung-Joo Plant Cell Reports, Vol.35 No.7, pp.1535-1544	DOI
2016-07	DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins Baek, Kwangryul; Kim, Duk Hyoung; Jeong, Jooyeon; Sim, Sang Jun; Melis, Anastasios; Kim, Jin-Soo; Jin, EonSeon; Bae, Sangsu Scientific Reports, Vol.6, p. 30620	DOI
2016-07	Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9 Park, Jeongbin; Kim, Jin-Soo; Bae, Sangsu Bioinformatics, Vol.32 No.13, pp.2017-2023	DOI
2016-11	Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease Lim, Youngbin; Bak, So Young; Sung, Keewon; Jeong, Euihwan; Lee, Seung Hwan; Kim, Jin-Soo; Bae, Sangsu; Kim, Seong Keun Nature Communications, Vol.7, p. 13350	DOI
2016-11	SIRT1-mediated downregulation of p27(Kip1) is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells He, Meilan; Yuan, Hongfeng; Tan, Brandon; Bai, Rosemary; Kim, Heon Seok; Bae, Sangsu; Che, Lu; Kim, Jin-Soo; Gao, Shou-Jiang Oncotarget, Vol.7 No.46, pp.75698-75711	DOI
2017-01	Cas-analyzer: an online tool for assessing genome editing results using NGS data Park, Jeongbin; Lim, Kayeong; Kim, Jin-Soo; Bae, Sangsu Bioinformatics, Vol.33 No.2, pp.286-288	DOI
2017-06	Digenome-seq web tool for profiling CRISPR specificity Park, Jeongbin; Childs, Liam; Kim, Daesik; Hwang, Gue-Ho; Kim, Sunghyun; Kim, Sang-Tae; Kim, Jin-Soo; Bae, Sangsu Nature Methods, Vol.14 No.6, pp.548-549
2017-06	CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection Kim, Heon Seok; Lee, Kyungjin; Bae, Sangsu; Park, Jeongbin; Lee, Chong-Kyo; Kim, Meehyein; Kim, Eunji; Kim, Minju; Kim, Seokjoong; Kim, Chonsaeng; Kim, Jin-Soo Journal of Biological Chemistry, Vol.292 No.25, pp.10664-10671	DOI
2017-07	Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression Koo, Taeyoung; Yoon, A-Rum; Cho, Hee-Yeon; Bae, Sangsu; Yun, Chae-Ok; Kim, Jin-Soo Nucleic Acids Research, Vol.45 No.13, pp.7897-7908	DOI
2017-11	Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors Yu, Nam-Kyung; Uhm, Heesoo; Shim, Jaehoon; Choi, Jun-Hyeok; Bae, Sangsu; Sacktor, Todd Charlton; Hohng, Sungchul; Kaang, Bong-Kiun Molecular Brain, 10(1):56	view file DOI
2018-04	Response to "unexpected mutations after CRISPR-Cas9 editing in vivo Kim, Sang-Tae; Park, Jeongbin; Kim, Daesik; Kim, Kyoungmi; Bae, Sangsu; Schlesner, Matthias; Kim, Jin-Soo Nature Methods, Vol.15 No.4, pp.239-240	DOI
2018-07	Direct observation of DNA target searching and cleavage by CRISPR-Cas12a Jeon, Yongmoon; Choi, You Hee; Jang, Yunsu; Yu, Jihyeon; Goo, Jiyoung; Lee, Gyejun; Jeong, You Kyeong; Lee, Seung Hwan; Kim, In-San; Kim, Jin-Soo; Jeong, Cherlhyun; Lee, Sanghwa; Bae, Sangsu Nature Communications, Vol.9, p. 2777	view file DOI
2018-12	Machine learning finds Cas9-edited genotypes Bae, Sangsu; Kim, Jin-Soo Nature Biomedical Engineering, Vol.2 No.12, pp.892-893	DOI
2018-12	Web-based design and analysis tools for CRISPR base editing Hwang, Gue-Ho; Park, Jeongbin; Lim, Kayeong; Kim, Sunghyun; Yu, Jihyeon; Yu, Eunchong; Kim, Sang-Tae; Eils, Roland; Kim, Jin-Soo; Bae, Sangsu BMC Bioinformatics, Vol.19, p. 542	DOI
2019-05	CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells Gruffaz, Marion; Yuan, Hongfeng; Meng, Wen; Liu, Hui; Bae, Sangsu; Kim, Jin-Soo; Lu, Chun; Huang, Yufei; Gao, Shou-Jiang mBio, Vol.10 No.3, p. e00866-19	view file DOI
2019-08	CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors Lee, Choongil; Jo, Dong Hyun; Hwang, Gue-Ho; Yu, Jihyeon; Kim, Jin Hyoung; Park, Se-eun; Kim, Jin-Soo; Kim, Jeong Hun; Bae, Sangsu Molecular Therapy, Vol.27 No.8, pp.1364-1371	DOI
2019-10	Adenine base editors catalyze cytosine conversions in human cells Kim, Heon Seok; Jeong, You Kyeong; Hur, Junho K.; Kim, Jin-Soo; Bae, Sangsu Nature Biotechnology, Vol.37 No.10, pp.1145-1148	DOI
2020	CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells Hwang, Gue-Ho; Yu, Jihyeon; Yang, Soyeon; Son, Woo Jae; Lim, Kayeong; Kim, Heon Seok; Kim, Jin-Soo; Bae, Sangsu Computational and Structural Biotechnology Journal, Vol.18, pp.1686-1694	DOI
2020-07	Purification of an Intact Human Protein Overexpressed from Its Endogenous Locus via Direct Genome Engineering Yu, Jihyeon; Cho, Eunju; Choi, Yeon-Gil; Jeong, You Kyeong; Na, Yongwoo; Kim, Jong-Seo; Cho, Sung-Rae; Woo, Jae-Sung; Bae, Sangsu ACS Synthetic Biology, Vol.9 No.7, pp.1591-1598	DOI
2021-07	PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing Hwang, Gue-Ho; Jeong, You Kyeong; Habib, Omer; Hong, Sung-Ah; Lim, Kayeong; Kim, Jin-Soo; Bae, Sangsu Nucleic Acids Research, Vol.49 No.W1, pp.W499-W504	DOI
2021-08	High-purity production and precise editing of DNA base editing ribonucleoproteins Jang, Hyeon-Ki; Jo, Dong Hyun; Lee, Seu-Na; Cho, Chang Sik; Jeong, You Kyeong; Jung, Youngri; Yu, Jihyeon; Kim, Jeong Hun; Woo, Jae-Sung; Bae, Sangsu Science Advances, Vol.7 No.35	DOI
2021-09	Web-based CRISPR Toolkits: Cas-OFFinder, cas-designer, and cas-analyzer Hwang, Gue-Ho; Kim, Jin-Soo; Bae, Sangsu Methods in molecular biology (Clifton, N.J.), Vol.2162, pp.23-33	DOI
2021-11	Adenine base editor engineering reduces editing of bystander cytosines Jeong, You Kyeong; Lee, SeokHoon; Hwang, Gue-Ho; Hong, Sung-Ah; Park, Se-eun; Kim, Jin-Soo; Woo, Jae-Sung; Bae, Sangsu Nature Biotechnology, Vol.39 No.11, pp.1426-1433	DOI
2022-07	Identification and Characterization of PSEUDO-RESPONSE REGULATOR (PRR) 1a and 1b Genes by CRISPR/Cas9-Targeted Mutagenesis in Chinese Cabbage (Brassica rapa L.) Kim, Nan-Sun; Yu, Jihyeon; Bae, Sangsu; Kim, Hyang Suk; Park, Soyoung; Lee, Kijong; Lee, Soo In; Kim, Jin A. International Journal of Molecular Sciences, Vol.23 No.13, p. 6963	DOI
2022-08	Therapeutic base editing and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa Hong, Sung-Ah; Kim, Song-Ee; Lee, A-Young; Hwang, Gue-Ho; Kim, Jong Hoon; Iwata, Hiroaki; Kim, Soo-Chan; Bae, Sangsu; Lee, Sang Eun Molecular Therapy, Vol.30 No.8, pp.2664-2679	DOI
2022-09	Genome Editing of Golden SNP-Carrying Lycopene Epsilon-Cyclase (LcyE) Gene Using the CRSPR-Cas9/HDR and Geminiviral Replicon System in Rice Kim, Jong Hee; Yu, Jihyeon; Kim, Hee Kyoung; Kim, Jin Young; Kim, Me-Sun; Cho, Yong-Gu; Bae, Sangsu; Kang, Kwon Kyoo; Jung, Yu Jin International Journal of Molecular Sciences, Vol.23 No.18, p. 10383	DOI
2022-09	Voyage to minimal base editors Song, Beomjong; Bae, Sangsu Nature Chemical Biology, Vol.18 No.9, pp.920-921	DOI
2023-01	Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches Kwon, Jeonghun; Kim, Minyoung; Hwang, Woochang; Jo, Anna; Hwang, Gue-Ho; Jung, Minhee; Kim, Un G.; Cui, Gang; Kim, Heonseok; Eom, Joon-Ho; Hur, Junho K.; Lee, Junwon; Kim, Youngho; Kim, Jin-soo; Bae, Sangsu; Lee, Jungjoon K. Genome Biology, 24(4)	view file DOI
2023-02	Enhancement of Gene Editing and Base Editing with Therapeutic Ribonucleoproteins through In Vivo Delivery Based on Absorptive Silica Nanoconstruct Kim, Seongchan; Jeong, You Kyeong; Cho, Chang Sik; Lee, SeokHoon; Sohn, Chang Ho; Kim, Jeong Hun; Jeong, Youngdo; Jo, Dong Hyun; Bae, Sangsu; Lee, Hyojin Advanced Healthcare Materials, Vol.12 No.4, p. 2201825	DOI
2023-03	Visual function restoration in a mouse model of Leber congenital amaurosis via therapeutic base editing Jo, Dong Hyun; Jang, Hyeon-Ki; Cho, Chang Sik; Han, Jun Hee; Ryu, Gahee; Jung, Youngri; Bae, Sangsu; Kim, Jeong Hun Molecular Therapy - Nucleic Acids, Vol.31, pp.16-27	DOI
2023-05	In vivo application of base and prime editing to treat inherited retinal diseases Jo, Dong Hyun; Bae, Sangsu; Kim, Hyongbum Henry; Kim, Jin-Soo; Kim, Jeong Hun Progress in Retinal and Eye Research, Vol.94, p. 101132	DOI
2023-10	NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells Shim, Ju A.; Lee, So Min; Jeong, Jin Woo; Kim, Hyori; Son, Woo Jae; Park, Jun Hong; Song, Parkyong; Im, Sin-Hyeog; Bae, Sangsu; Park, Jung-Hyun; Jo, Yuna; Hong, Changwan Cell Communication and Signaling, Vol.21(1):309	view file DOI
2024-09	Discovery of novel disease-causing mutation in SSBP1 and its correction using adenine base editor to improve mitochondrial function Cha, Ju Hyuen; Lee, Seok-Hoon; Yun, Yejin; Choi, Won Hoon; Koo, Hansol; Jung, Sung Ho; Chae, Ho Byung; Lee, Dae Hee; Lee, Seok Jae; Jo, Dong Hyun; Kim, Jeong Hun; Song, Jae-Jin; Chae, Jong-Hee; Lee, Jun Ho; Park, Jiho; Kang, Jin Young; Bae, Sangsu; Lee, Sang-Yeon Molecular Therapy - Nucleic Acids, Vol.35 No.3, p. 102257	DOI
2025	Optimizing HDAC inhibitors to enhance HDR-associated CRISPR-Cas9 gene editing efficiency in vivo and in vitro Jang, Jeong Woon; Kim, Min Ji; Cho, Chang Sik; Han, Jun Hee; Bae, Sangsu; Jeon, Hongjun; Jo, Dong Hyun; Nam, Hye Jin Heliyon, Vol.11 No.5, p. e42971	DOI
2025-03	Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing Lim, Jina; Lee, Namseok; Ju, Seonmin; Kim, Jeesoo; Mun, Subin; Jeon, Moonhyeon; Lee, Yong-ki; Lee, Seok-Hoon; Ku, Jayoung; Kim, Sujin; Bae, Sangsu; Kim, Jong-Seo; Kim, Yoosik Communications Biology, Vol.8 No.1, p. 389	DOI
2025-04	Autophagy induction enhances homologous recombination-associated CRISPR-Cas9 gene editing Nam, Hye Jin; Han, Jun Hee; Yu, Jihyeon; Cho, Chang Sik; Kim, Dongha; Kim, Young Eun; Kim, Min Ji; Kim, Jeong Hun; Jo, Dong Hyun; Bae, Sangsu Nucleic Acids Research, Vol.53 No.7, p. gkaf258	DOI
2025-06	Bystander editing by adenine base editors impairs vision restoration in a mouse model of Leber congenital amaurosis Lee, Seok-Hoon; Wu, Jun; Im, Dongjoon; Hwang, Gue-ho; Jeong, You Kyeong; Jiang, Hui; Lee, Seok Jae; Jo, Dong Hyun; Goddard III, William A.; Kim, Jeong Hun; Bae, Sangsu Molecular Therapy - Methods and Clinical Development, Vol.33 No.2, p. 101461	DOI